Yes, several alternatives to CFCs have been developed, including hydrofluorocarbons (HFCs) and hydrochlorofluorocarbons (HCFCs). While HFCs do not deplete the ozone layer, they are potent greenhouse gases and contribute to global warming. Consequently, efforts are underway to develop and adopt more environmentally friendly substances, such as hydrofluoroolefins (HFOs), which have lower global warming potentials.